— Transgenic mouse strain designed and developed by Dr. Conrad Weihl with a mutation of the DNAJB6 gene at the F90I protein. This homologous with the human form of muscular dystrophy with patients having a genetic variant at the F89I protein.
— Technology Description
Researchers at Washington University in St. Louis have developed a prognostic biomarker that can be used to predict response to genotoxic chemotherapy for patients with basal-like/triple-negative breast cancer. Basal-like/triple-negative breast cancer is considered to be mor…
— An UPAB1 derivative, UPAB1p-, that spontaneously loss pAB5 was identified by detection of restored Hcp secretion and isolated via an ELISA.
Compared to wildype UPAB1, UPAB1p- displayed comparable growth in vitro in both rich medium and urine from healthy donors, indicating that less pAB5 did not in…
— MCB6A organoids generate urothelial tumors with features similar to the basal-squamous subtype of urothelial carcinoma, the most common bladder cancer. MCB6A harbors 1,524 mutations, including mutations in Kdm6a and Trp53.
Publication: CD4+ T cells induce rejection of urothelial tumors after imm…
— Technology Description
Researchers in Prof. Mario Feldman’s laboratory have developed a patented, versatile, cost-effective platform for creating new multivalent vaccines for a variety of Gram-negative and Gram-positive bacteria. This technology, glycoengineered outer membrane vesicles (geOM…
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Creating...
