— CRISPR-Cas9 gene editing was used to modify the coding region of the NMI mouse gene. The genetic modification resulted in the deletion of the full length production of the protein. This modification was made the C57BL/6J genetic background. NMI is a host protein involved in innate immune signaling a…
— CRISPR-Cas9 gene editing was used to modify the coding region of the SAMD9L mouse gene. The genetic modification resulted in the deletion of the full length production of the protein. This modification was made in a C57BL/6 genetic background.
— These set of plasmids allow for the repression and de-repression of fluorescent proteins (GFP and mCherry) through CRISPR interference and antisense RNA.
Publication: Programmable control of bacterial gene expression with the combined CRISPR and antisense RNA system
— These plasmids contain target binding regions (TBRs) targeting rfp that were placed under the control of pTet via blunt end lifgation. Hfq binding sites that had been identified from the literature were inserted adjacent to the TBR sequence using either blunt end ligation or Golden Gate assembly, de…
— This technology contains a set of patient derived xenograft cell lines. These cell lines represent the heterogeneity of human malignant peripheral nerve sheath tumors (MPNSTs) that can be used to test novel agents to move forward into clinical trials.
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