by | Mar 10, 2018 | Lanza, Gregory, Pan, Dipanjan, Senpan, Angana, Wickline, Samuel
— Background: Biodegradable magnetic carriers have been increasingly utilized in biomedical and clinical research, but the larger size of ferromagnetic agents previously used leads to long circulation times and restriction to the vasculature, making these particles ideally suited for detection of spa…
by | Mar 10, 2018 | Becker, Matthew, Fang, Huafeng, Pan, Dipanjan, Rossin, Raffaella, Sun, Xiankai, Taylor, John-Stephen, Turner, Jeffrey, Welch, Michael, Wooley, Karen
— This invention features cell permeable nano conjugates of shell-cross-linked knedel (SCK) and peptide nucleic acids (PNA) with mRNA targeting sequences for early diagnosis and therapy of cancers.