— Technology Description
Researchers in Prof. Amit Pathak’s laboratory have developed a hydrogel system that utilizes an aldehyde-based compound to easily and reliably pre-functionalize polyacrylamide for conjugation of proteins, such as collagen and fibronectin, for cell culture applications.…
— Disease Indications
Drug type: Biologic – engineered protein
Drug class: First in class
Technology:
A recombinant fusion protein that depletes B cells in the recipient that are specific to the donor HLA. The fusion protein offers a targeted therapy for antibody-mediated rejection in the …
— Technology Description:
Researchers at Washington University have developed a method that allows the transduction of full-length proteins by utilizing the pTAT or pTAT-HA protein expression plasmids. A protein of choice can be fused to a HIV-TAT transduction domain under the expression system. Ba…
— Technology Description: In collaboration with the scientists at Broad Institute, WU scientists have developed a new software with a new algorithm that enables HLA high resolution typing from exome sequencing data. It will provide a significantly better tool to guide the bone marrow transplantation a…
— The prevalence of hearing loss (HL) in adolescents has grown over the past decade, with rates of 19.5% for HL of >15dB and 5.3% for HL >25dB. Adults with HL are 21% to 39% less likely to have attained postsecondary education than normal-hearing persons and are 1.5 to 2 times more likely to exp…
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