by | May 28, 2020 | Guruswami, Sundaram, Sharma, Vijay, Sivapackiam, Jothilingam
— Technology Description
Researchers at Washington University in St. Louis have developed PET radiotracers to image amyloid beta (A-beta) at early stages of Alzheimer’s Disease (AD). For AD treatment to be effective, it may have to be administered during the preclinical stage. As such, there i…
by | May 15, 2020 | Bridgman, Paul, Turney, Stephen
— Technology Description
This technology is a patented method for producing microarrays or directing cell growth on a surface by precisely and dynamically manipulating the adhesion of macromolecules. While many techniques exist for adhering proteins, nucleic acids, and other macromolecules to solid …
by | May 5, 2020 | Mach, Robert, Tu, Zhude "Will", Wang, Wei
— Technology Description
Researchers at Washington University in St. Louis and their colleagues have developed positron emission tomography (PET) tracers with high affinity for sigma-1 receptors. Sigma receptors have two subtypes, sigma-1 and sigma-2. Sigma-1 has high expression in the limbic and mo…
by | Apr 27, 2020 | Cruchaga, Carlos, Dube, Umber, Ibanez, Laura
— Technology Description:
Researchers in Prof. Carlos Cruchaga’s laboratory have identified a sensitive and specific panel of circular RNAs (circRNA) that could be used for diagnosing, screening or monitoring patients with Alzheimer’s disease. The expression of these circRNAs tracks with …
by | Apr 8, 2020 | DiAntonio, Aaron, Milbrandt, Jeffrey
— Crispr developed SARM1 Knockout Rat