by | Dec 11, 2020 | Luhmann, Scott
— Technology Description:
Researchers at Washington University in St. Louis have identified blood-based cytokine signatures that could be used to specifically detect, distinguish and monitor septic arthritis, synovitis and osteomyelitis. This assay could enable timely, accurate treatment to avoid joi…
by | Nov 16, 2020 | Buchser, William, Lalli, Matthew, Milbrandt, Jeffrey, Mitra, Robi
— Technology Description
A team of Washington University researchers has developed a low-cost molecular diagnostics kit and reader that could provide rapid, widespread screening and surveillance for SARS-CoV-2 and other infections. This technology utilizes a reverse-transcription loop-mediated isot…
by | Sep 8, 2020 | Reck, Margaret, Schaffer, Jason, Wencewicz, Timothy
— Chemists from Washington University have discovered and characterized an enzyme pathway that could be harnessed as an efficient platform to produce peptide beta-lactone libraries for drug discovery. Beta-lactones are a family of molecules with a structure similar to penicillin and therefore could po…
by | Sep 4, 2020 | Storch, Gregory, Wylie, Kristine, Wylie, Todd
— Technology Description
A team of researchers at Washington University designed patented primers for a sensitive, specific, real-time reverse transcriptase PCR (RT-PCR) assay to quickly detect enterovirus D68 (EV-D68).
EV-D68 is an emerging, highly contagious respiratory virus that can cause seve…
by | Jul 16, 2020 | Feldman, Mario
— Technology Description
Researchers in Prof. Mario Feldman’s laboratory have developed a patented, versatile, cost-effective platform for creating new multivalent vaccines for a variety of Gram-negative and Gram-positive bacteria. This technology, glycoengineered outer membrane vesicles (geOM…