by | Apr 8, 2021 | Lichti, Cheryl, Unanue, Emil, Wan, Xiaoxiao
— Technology Description:
Researchers in the lab of Emil Unanue at Washington University have discovered a panel of peptides responsible for autoimmune activation in Type 1 diabetes and potentially capable of diagnosing T1D at an early stage. These peptide fragments of insulin are found circulating …
by | Sep 21, 2020 | Kaiko, Gerard, Liu, Ta-Chiang, Stappenbeck, Thaddeus
— Plasminogen activator inhibitor-1 (PAI-1) has been identified as a specific biomarker that is significantly elevated in patients with inflammatory bowel disease (IBD) and is correlated with disease severity. It could be used to both diagnose the disease (including ulcerative colitis and colonic Croh…
by | Sep 21, 2020 | Kaiko, Gerard, Liu, Ta-Chiang, Stappenbeck, Thaddeus
— Plasminogen activator inhibitor-1 (PAI-1) has been identified as a specific biomarker that is significantly elevated in patients with inflammatory bowel disease (IBD) and is correlated with disease severity. It could be used to both diagnose the disease (including ulcerative colitis and colonic Croh…
by | Sep 10, 2020 | Kim, Brian, Wang, Fang
— Researchers at Washington University’s Center for the Study of Itch & Sensory Disorders have discovered a novel histamine-independent pathway that could be targeted to treat atopic dermatitis.
Atopic dermatitis (AD) is a chronic inflammatory skin disease that presents with itch as its mos…
by | Aug 26, 2020 | Cao, Yu-Qing, Cloud, Megan, Hu, Rong, Zhang, Jintao, Zhang, Zhiyu
— Technology Description
Researchers at Washington University in St. Louis (WUSTL) have developed two methods for treating chronic migraine and post-traumatic headache. Chronic migraine and post-traumatic headache are highly prevalent and debilitating with limited treatment options. Further, for m…