— Background
Temperature differences between tumor and healthy tissue due to increased blood flow and metabolic activity are exploited for thermal imaging (TI) as an adjunct imaging modality for cancer diagnosis. Despite many technological advances and recent improvements, TI has a limited tumor dept…
— Description: Calcium Carbonate nanoparticles for normalizing tumor microenvironment
Publication: Som A, Raliya R, Tian L, Akers W, Ippolito JE, Singamaneni S, Biswas P, Achilefu S. Monodispersed calcium carbonate nanoparticles modulate local pH and inhibit tumor growth in vivo. Nanoscale. 2016 Jul …
— Fluorescent tagged octapeptide for cancer detection
— Technology Description: Macrocyclic Molecular Beacons Useful for Medical applications :US 20070098638 (published US application) : The sensitivity and specificity of the optical modality can be enhanced by the use of highly absorbing compounds as contrast agents. Novel macrocyclic cyanine and indocy…
— Background: Integrins are multi-subunit transmembrane proteins involved in a wide range of cellular processes including the induction of new blood vessel formation and tumor metastasis. The growth of new blood vessels, termed angiogenesis, is associated with an altered integrin expression profile wh…
— Background: Near Infrared (NIR) fluorescence can be highly useful in biological systems as it is highly sensitive and allows for detection and imaging of physiological and molecular processes in cells and living organisms. However, radiometric imaging is difficult in the NIR region of the light spec…
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