The present hydrogel technology can be used as a lens replacement material for the permanent treatment of cataracts and presbyopia as well as a vitreous substitute. This co-polymeric hydrogel system can be reversibly converted between a hydrogel in the oxidized state and a solution in the reduced state and mimics the optomechanical properties of the native lens and vitreous. Rabbit studies using the hydrogel system as a vitreous substitute indicate that the material can be injected into the eye, undergo gelation, remain optically clear, and remain well tolerated. Long-term biocompatibility and degradation studies are in progress.

Benefits:

• Permanent solution to cataracts, presbyopia, and vitroretinal pathologies.
• Minimally invasive and easily deliverable through injection.
• Can conform to fill native or potential cavities.
• Drugs and/or particles may be added to the system.