by | Jul 13, 2020 | Ory, Daniel, Peterson, Linda, Schaffer, Jean
— Technology Description
A team of researchers has developed a high throughput, FDA-compliant assay to predict coronary heart disease and mortality in the general population 6-10 years before the onset of disease. This fully validated two-dimensional liquid chromatography-tandem mass spectrometry (L…
by | Jul 13, 2020 | Millman, Jeffrey, Velazco-Cruz, Leonardo
— Technology Description
Researchers at Washington University in St. Louis have developed an improved method to differentiate stem-cells into functionally mature, insulin-secreting beta cells (SC-beta cells). Pancreatic beta cells play an important role in controlling blood glucose levels as they se…
by | Jul 9, 2020 | Gong, Yong-feng, Hou, Jianghui
— Disease indication: metabolic disorders including insulin resistance and diabetic nephropathy
Drug format: chemically modified synthetic microRNA (miRNA)
Drug class: first-in-class for metabolic disease
Research stage and Preliminary data:
Target: miR-29 mimics can increase the gene expressio…
by | Jun 26, 2020 | Ellebedy, Ali
— Species: Human
Target: SARS-CoV-2 nucleocapsid protein
Applications:
Description: Two recombinant fully human monoclonal antibodies that recognize SARS-CoV-2 spike protein (data below).
Related Web Links: Ellebedy Profile; Ellebedy Lab
by | Jun 26, 2020 | Diamond, Michael, Ellebedy, Ali, Fremont, Daved
— Species: Mouse
Target: SARS-CoV-2 spike protein
Applications:
Description: Four murine monoclonal antibodies that recognize SARS-CoV-2 spike protein. Data below includes avaiable antibodies (mCoV.1.1C02; mCoV.1.2C08; mCoV.1.2D09; mCoV.1.2F05).
Related Web Links: Ellebedy Profile; Ellebedy Lab
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