by | Dec 1, 2019 | Caparon, Michael, Flores-Mireles, Ana, Hultgren, Scott, Pinkner, Jerome
— Technology Description
Researchers at Washington University in St. Louis have developed a vaccine strategy to prevent catheter-associated urinary tract infections (CAUTIs). CAUTIs are the most common cause of hospital-acquired infections. Many of these are caused by Enterococcus bacteria. CAUTIs a…
by | Oct 22, 2019 | Finkbeiner, Stacy, Virgin, Herbert, Wang, David, Zhao, Guoyan
— Technology Description
A team of researchers at Washington University and the Centers for Disease Control discovered, sequenced and patented a novel human astrovirus that can cause encephalitis and gastroenteritis (non-etiologic diarrhea), offering a path to detection and diagnostics.
The virus (…
by | Oct 22, 2019 | Basore, Katherine, Diamond, Michael, Fremont, Daved, Kim, Arthur, Nelson, Christopher, Thackray, Larissa, Zhang, Rong
— Technology Description
Researchers at Washington University in St. Louis have identified a target for therapeutic development and created methods to potentially treat arthritogenic alphavirus infection. Arthritogenic alphaviruses, including chikungunya (CHIKV), Ross River, Mayaro and O’nyong…
by | Oct 22, 2019 | Curiel, David
— Disease indication – Cancer
Drug format – Adenoviral vector for immunotherapy/dendritic cell therapy
Drug class – Improvement
Research stage and Preliminary data:
Target – Carbohydrate biomarkers of cancer
Background:
Dendritic cells (DCs) are potent antigen presenting cell…
by | Mar 10, 2018 | Lam, Woei Chuan, Lodge, Jennifer, Upadhya, Rajendra
— Cryptococcus fungi are pathogenic fungi that, unless treated, are invariably fatal to those individuals infected, particularly to those who are immunocompromised. Recent reports indicate that Cryptococcus fungi infects 1,000,000 individuals per year and causes approximately 600,000 deaths. While ant…