by | Oct 22, 2019 | Berezin, Mikhail, Binkley, Michael, Meacham, John
— Technology Description:
Methods and devices used for acoustophoresis of biologics have been developed and allow for more than 10,000 fold throughput than existing acoustophoretic devices.
Applications:
1. Isolation of cells in low abundance (immune cells, circulating tumor cells) from whole bloo…
by | Oct 22, 2019 | Apte, Rajendra
— Technology Description
Researchers in Prof. Rajendra Apte’s laboratory developed novel methods for treating macular degeneration and other eye diseases by targeting a cholesterol transport pathway involved in the formation of new blood vessels. Age-related macular degeneration (AMD) is a lea…
by | Oct 22, 2019 | Abernathy, Daniel, Yoo, Andrew
— Background: Studying late-onset neurodegenerative disorders using patient-specific neurons is one of the primary goals of precision medicine. The ability to generate human neurons that mimic the neurons of elderly individuals will provide an instrumental platform to model and study adult-onset neuro…
by | Oct 22, 2019 | Kotzbauer, Paul, Li, Junfeng, Tu, Zhude "Will", Yue, Xuyi
— Compounds with high affinity for aggregated alpha-synuclein, after radiolabeling with C-11 or F-18, 1- 125, 1-123 and Br-76, could be used as PET tracers to measure the level and distribution of aggregated alpha-synuclein in patients with Parkinson’s disease and related diseases such as DLB…
by | Oct 22, 2019 | Klechevsky, Eynav
— Background
Dendritic cells (DCs) are antigen-presenting cells that are essential to the adaptability of the immune system. Several subsets of DCs have been identified in tissues that interface with the environment (e.g. skin, mucosal lining). While the role of specific DC subsets are unknown, DCs p…