ME1 Deficiency Primes for Ferroptosis

— Background: Synovial sarcoma is a rare soft tissue sarcoma that most commonly affects young adults. Like many other cancers, there are currently no targeted chemotherapies for synovial sarcoma. Current treatment often consists of a combination of surgery, radiation therapy, and chemotherapy. The met…

ME1 Deficiency Primes for Ferroptosis

— Background: Synovial sarcoma is a rare soft tissue sarcoma that most commonly affects young adults. Like many other cancers, there are currently no targeted chemotherapies for synovial sarcoma. Current treatment often consists of a combination of surgery, radiation therapy, and chemotherapy. The met…

IP-10 as a blood biomarker of respiratory failure

— Technology Description

Researchers in Philip Mudd’s lab at Washington University have developed a blood biomarker test that detects impending respiratory failure before existing diagnostics. High levels of the biomarker IP-10 in the blood are correlated with the subsequent development of acu…

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