by | Jun 18, 2024 | Ali, Muhammad, Cruchaga, Carlos
— Technology Description
Researchers at Washington University in St. Louis have developed models that can very accurately predict brain amyloidosis—Alzheimer’s disease status. Alzheimer’s disease (AD) is characterized by the accumulation of Amyloid-β (Aβ42) and hyperphos…
by | May 15, 2024 | DiAntonio, Aaron, Geisler, Stefanie, Mao, Xianrong, Milbrandt, Jeffrey, Summers, Daniel
— Value Proposition: This invention uses a novel gene therapy that blocks the axon degeneration typical of neurodegenerative diseases.
Technology Description
Researchers at Washington University in St. Louis have developed a new strategy for treatment of neurodegenerative diseases with axonopathy…
by | Feb 21, 2024 | Luff, Stephanie, Sturgeon, Christopher
— T-018886 — Scalable Generation of Hematopoietic Progenitors from Human Pluripotent Stem Cells
Technology Description
In vitro generation of CD34+ hematopoietic progenitor cells (HPC) that faithfully recapitulate in vivo behavior is an area of ongoing research. A key characteristic of CD34+ …
by | Jul 21, 2022 | Cohen, Barak, Zhao, Siqi
— Technology Description
Researchers in Barak Cohen’s lab at Washington University have developed a method for single cell massively parallel reporter assay (scMPRA) to preserve cell type-specific information. This technology is scalable and sequencing platform agnostic.
Massively parallel…
by | Mar 10, 2022 | Kremer, Jeff, Lange, Sara, Van Tine, Brian
— Background: Synovial sarcoma is a rare soft tissue sarcoma that most commonly affects young adults. Like many other cancers, there are currently no targeted chemotherapies for synovial sarcoma. Current treatment often consists of a combination of surgery, radiation therapy, and chemotherapy. The met…