— D42m1 is a methycholanthrene (MCA) induced sarcoma cell line generated in 129S6 strain RAG2 gene targeted mice. These cells are highly immunogenic and are rejected when transplanted into syngeneic naive wild type mice.
F244 is an MCA induced sarcoma cell line generated in wild type 129S6 mice. Thes…
— Target: Type-1 interferon receptor subunit, a key signaling receptor in the interferon pathway.
Notes: Clones MAR1-5A3, MAR1 -1H5, MAR1-3A7, MAR1-4D12, MAR1-4F12
Publication:
— Two plasmids each containing a single murine mutant tumor neoantigen:
a) retroviral MSCV-IRES encoding full length mutant lamanin alpha 4 (mLama4)
b) retroviral MSCV plasmid encoding full length mutant integrin beta 1 (mItgb1)
— Description: HDbeta-4A7- mouse IgG2a monoclonal antibody reactive with murine Interferon-beta. This mAb has neutralizing activity.
Publication:
— Description: TIF-3C5- Armenian hamster monoclonal antibody reactive with murine Type I Interferons, including IFN alpha A, 1, 4, 5, 11 and 13 but not IFNbeta. This mAb can block functional activity.
Publication:
— Target: C-X-C chemokine family member (CXCR3). Expressed on NK cells, activated T lymphocytes, select
endothelial and epithelial cells.
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