Mice with Mutant Gtf2i and Gtf2ird1 Alleles
— Dr. Dougherty developed a collection of mouse lines with deletions of Gft2i and Gtfird1 in various combinations. The genes are related to Williams Beuren locus.
Publications:
Egr1Cre;Snap25Flp mice (On deposit with Jackson Labs – Strain 033895)
— Egr1Cre;Snap25Flp mice
microRNA biomarker and drug target for ALS and other motor neuron diseases
— Prof. Timothy Miller and colleagues have identified a motor neuron-specific, drug responsive microRNA (miR-218) that reflects the pathology of amyotrophic lateral sclerosis (ALS). This biomarker could be a target for therapeutic intervention or a proxy for motor neuron health and survival, including…
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