by | May 1, 2024 | Adams, Lucas, Diamond, Michael, Fremont, Daved, Raju, Saravanan
— VLDLR-based Decoy Receptors to Prevent Alphavirus Infections
Technology Description
Researchers at Washington University in St. Louis have developed very low-density lipoprotein receptor (VLDLR) soluble decoy receptors with potent inhibitory activity in vitro and in vivo. Eastern equine encephali…
by | Apr 29, 2021 | Adams, Lucas, Diamond, Michael, Fremont, Daved, VanBlargan, Laura
— Disease indication – SARS-CoV-2 infection (COVID-19)
Drug format – Chimeric monoclonal antibody
Drug class – Best-in-class
Research stage and Preliminary data – The inventors have developed and characterized this antibody, creating a chimeric version with a human IgG backbone. T…