— CRISPR-Cas9 gene editing was used to modify the coding region of the SAMD9L mouse gene. The genetic modification resulted in the deletion of the full length production of the protein. This modification was made in a C57BL/6 genetic background.

— These are recombinant human monoclonal antibodies that are directed against two conserved internal proteins of the influenza virus.

— pRRLsinPGK-GFPppt : Plasmid DNA directing expression of green fluorescent protein in a lentiviral shuttle vector under the control of the phosphoglycerate kinase (PGK) promoter. FCIV: Plasmid DNA directing expression of Venus (a fluorescent protein) in a lentiviral shuttle vector under the control o…

— CRISPR-Cas9 gene editing was used to modify the coding region of the NMI mouse gene. The genetic modification resulted in the deletion of the full length production of the protein. This modification was made the C57BL/6J genetic background. NMI is a host protein involved in innate immune signaling a…

— CRISPR-Cas9 gene editing was used to modify the coding region of the MAP3K6 mouse gene. The genetic modification resulted in the deletion of the full length production of the protein. This modification was made in a C57BL/6J genetic background. MAP3K6 is a signaling molecule and could be the target …

— A plasmid based reverse genetics system for Bourbon virus was created. This system and related plasmids allow for the creation of infectious Bourbon virus and evaluate the impact of genetic variation on the virus (replication, disease, antibody-mediated neutralization etc.). It also allows for the c…

— MDK is a molecular target for treatment of cancer. These antibodies are to the functional domain of MDK.

— Neuronal cell line lacking Wfs1 gene by CRISPR/CAS9

— Pancreatic beta cell line lacking Wfs1 gene created by CRISPR/CAS9

— This mouse strain is a novel Natural Killer cell specific inducible cre that is useful for studying the development, maturation, and function of NK cells. It has a tamoxifen inducible Ncr1-ERT2iCre mouse allele that is used for floxing gene(s) of interest out of NK cells. This model was designed, cr…

— Technology Description Researchers in Prof. Jeffrey Henderson’s laboratory have discovered a drug target and a class of small molecule candidates that could be used to selectively prevent pathogenic enterobacteria from causing diseases such as urinary tract infections (UTIs). Currently, UTI…

— Target: Cluster of Differentation 355 protein, a.k.a. Cytotoxic and Regulatory T-Cell Molecule. Notes: Clone available is 134.

— Target: Cluster of Differentation 177 protein, a.k.a. Neutrophil Specific Antigen 1. Notes: Clone available is 4127.

— Target: Cluster of Differentation 355 protein, a.k.a. Cytotoxic and Regulatory T-Cell Molecule. Notes: Clone available is Cr 24.1. Used in flow cytometry.Monoclonal antibody to human CRTAM Monoclonal antibody (mAb) Cr24.1 was generated by immunizing BALB/c mice with CRTAM-P815 cells. Cells were injected bilaterally 4 times at weekly intervals into the hind leg. Cytosine-phosphate-guanosine (CpG) oligonucleotide was used as adjuvant (CpG 1826, 25 …

— Mouse model for Niemann-Pick C1 (NPC1) disease This mouse model was generated by CRISPR KI of the P1007A mutation into the NPC1 protein. Mice heterozygous or homozygous for this mutation do not have an apparent phenotype. However, when the heterozgous P1007A mouse is crossed with the NPC1 I1061T m…

— To generate the mice, the researchers micro-injected ES cell clones carrying the targeted allele B2mtm1a(EUCOMM)Hmgu (B2mtm1a) into Albino B6 blastocysts.Chimeric mice were bred to Albino B6 to identify germline transmission by coat color. Mice containing the germline-transmitted B2mtm1a allele were…

— These plasmids are for performing CRISPR/Cas9 gene editing in Cryptosporidium parvum To generate a CRISPR/Cas9 plasmid for use in C. parvum, researchers used restriction cloning with SacI to insert the C. parvum U6 gene into a pUC19 vector to create pUC19-CpU6. We then inserted the C. parvum actin …

— This human cell line is a generic source for culturing Toxoplasma gondii in the laboratory. It was generated by Michael White’s laboratory.

— These induced pluripotent stem cell reporter cell lines were generated by introducing the following fluorescent reporters at the indicated loci: BJFF6 cells were modified with CRISPR/Cas9 to generate these cell lines.

— Target: C-X-C chemokine family member (CXCR3). Expressed on NK cells, activated T lymphocytes, select endothelial and epithelial cells.Hamsters were immunized with a multiple antigens peptide-8 (MAPS-8) encompassing amino acids 1 to 37 of mouse CXCR3 in complete Freund’s adjuvant, and boosted with peptide in incomplete Freund’s adjuvant. Hamsters showing ELISA seropositivity for CXCR3 peptide were boosted and hybridomas gen…