by | Jul 24, 2024 | Barratt, Michael, Chang, Hao-Wei, Gordon, Jeffrey, Hibberd, Matthew, Wang, Yi, Webber, Daniel
— Value Proposition: Human microbe strains with robust colonization efficacy and potent in vivo harvesting of beneficial metabolites involved in infant health.
Technology Description
Researchers from the laboratory of Dr. Jeffrey Gordon at Washington University in St. Louis have discovered str…
by | Mar 30, 2022 | Gelman, Andrew, Puyo, Carlos
— Technology Description
Researchers at Washington University in St. Louis have developed a drug combination that can be used to prevent tissue injury resulting from placement of a variety of medical devices including, but not limited to, endotracheal tubes (ETTs) and catheters (bladder catheters). P…
by | Mar 22, 2022 | Covey, Douglas, Jiang, Xin
— Technology Description
Researchers at Washington University have developed a range of steroid anesthetic agents that share known neurosteroid structures but are more potent. These compounds share the basic structure of neurosteroids alphaxalone, allopregnanolone, and ent-androsterone, but the stru…
by | Mar 9, 2022 | Alhallak, Kinan, Azab, Abdel Kareem
— Disease indication – multiple myeloma
Drug format – antibodies conjugated to nanoparticles for T-cell immunotherapy
Drug class – improved delivery platform
Research stage and Preliminary data:
In vivo:
In vitro proof of concept – in a MM cell line: NanoMuTEs and NanoTC…
by | Feb 18, 2022 | Kreple, Collin, Miller, Timothy, Nielsen, Susan, Racette, Brad
— Technology Description
Researchers in Brad Racette and Tim Miller’s labs at Washington University have developed a therapeutic strategy for treating ALS by using statins to lower LDL. Statins were successful at prolonging both survival and time with a normal gait.
The researchers identif…