by | Nov 14, 2019 | Nichols, Colin, Remedi, Maria
— This is a CRISPR/Cas9 germline mutation in the KCNJ8 gene, equivalent to a human Cantu Syndrome mutation. The mouse is therefore a genetic model of human Cantu Syndrome. This mouse model can be used for pre-clinical testing of targeted therapy for Cantu Syndrome.
Publication: Cardiovascular consequ…
by | Nov 14, 2019 | Nichols, Colin, Remedi, Maria
— This mouse model was generated by using CRISPR/Cas9 to mutate the ABCC9 gene. The mouse model described here could be used as a pre-clinical model for testing Cantu Syndrome therapies.
Publication: Cardiovascular consequences of KATP overactivity in Cantu syndrome
by | Oct 22, 2019 | Gordon, Jeffrey, Turnbaugh, Peter
— Technology Summary:
Obesity rates worldwide are increasing at an astounding rate. While diet, lifestyle, and physical activity have traditionally been identified as the main causative factors, researchers at Washington University are the first to implicate gut bacteria (microbiome) as a new drivin…
by | Oct 22, 2019 | Miner, Jeffrey
by | Oct 22, 2019 | Barratt, Michael, Chang, Hao-Wei, Gehrig, Jeanette, Gordon, Jeffrey, Venkatesh, Siddarth
— Technology Description
Prof. Jeffrey Gordon and his colleagues have developed an inexpensive food formulation that could treat malnutrition and a range of associated health problems by repairing the gut microbiome. Children who are malnourished are currently treated with supplemental nutrition tha…