by | Dec 1, 2019 | Covey, Douglas, Izumi, Yukitoshi, Zorumski, Charles
— Technology Description
Researchers from Washington University in St. Louis and colleagues have identified ent-allopregnanolone (ent-AlloP) as a potential therapeutic to treat glaucoma. Glaucoma, the leading cause of irreversible blindness, results from damage to the retinal ganglion cells (RGSs) t…
by | Nov 27, 2019 | Fehniger, Todd
— This mouse strain is a novel Natural Killer cell specific inducible cre that is useful for studying the development, maturation, and function of NK cells. It has a tamoxifen inducible Ncr1-ERT2iCre mouse allele that is used for floxing gene(s) of interest out of NK cells. This model was designed, cr…
by | Nov 27, 2019 | Hallahan, Dennis, Kapoor, Vaishali
— MDK is a molecular target for treatment of cancer. These antibodies are to the functional domain of MDK.
by | Nov 20, 2019 | Morris, Samantha
— Plasmid with fused Hnf4a and Foxa1 genes to express as a single transcript. Individual genes were obtained from Addgene.
by | Nov 14, 2019 | Nichols, Colin, Remedi, Maria
— This mouse model was generated by using CRISPR/Cas9 to mutate the ABCC9 gene. The mouse model described here could be used as a pre-clinical model for testing Cantu Syndrome therapies.
Publication: Cardiovascular consequences of KATP overactivity in Cantu syndrome