by | Apr 29, 2020 | Bach, Richard, Boyle, Walter
— Background: Cardiovascular disease, including acute myocardial injury (AMI), is responsible for over 610,000 deaths per year in the US making it the number one cause of death. The gold standard for AMI diagnosis relies on determination of the cardiac troponin I (cTnI) plasma level. The rise in the l…
by | Apr 6, 2020 | Storch, Gregory, Wylie, Kristine, Wylie, Todd
— Technology Description
A team of researchers at Washington University developed “ViroCap”, a patented capture probe technique for senistive, comprehensive, in-depth metagenomics analysis vertebrate viruses. This invention could enhance traditional metagenomics shotgun sequencing (MSS) w…
by | Jan 31, 2020 | Tolia, Niraj
— Plasmid comprising the signal peptide and extracellular domain of human glycophorin A fused to antibody Fc domain and a his tag. This plasmid has been used to study malaria treatments.
Publications:
by | Jan 15, 2020 | Boyle, Walter
— Background: Vasodilatory shock, a reduction in effective blood circulation, occurs when endogenous vasoconstrictor mechanisms fail as a result of an often lethal combination of severe infections. Sepsis, as one of the causes, alone affects 1 million people resulting in more than 258,000 deaths each …
by | Dec 18, 2019 | Humphreys, Benjamin
— Researchers used CRISPR/Cas9-mediated gene targeting to knock in a GFP-P2A cassette into the ATG of the Six2 gene in human BJFF.6 induced pluripotent stem cells. The cells exhibit GFP expression in Six2+ cells when induced to differentiate towards the renal lineage. Six2 expression marks a progenito…