by | Jun 11, 2024 | Janetka, James, Mitreva, Makedonka
— Novel Composition Designed to Treat Nematode Infections
Value proposition: Small molecule treatments designed to target the adult worm to treat nematode infections in animals.
Technology Description
Researchers at Washington University in St. Louis have developed novel small molecule treatment…
by | Jun 11, 2024 | Berezin, Mikhail, Birman, Vladimir, Fuentes, Isaac
— Value proposition: Fluorescent oxonol dyes that can be used to enhance bioimaging for the treatment of cancer.
Technology Description
Researchers at Washington University in St. Louis have developed a new class of fluorescent oxonol dyes that exhibit absorption and emission in the near infrared…
by | Jul 26, 2022 | Amin, Neha, Borcherding, Dana, Hirbe, Angela
— Technology Description
Researchers in Angela Hirbe’s lab at Washington University have developed a method of treating malignant peripheral nerve sheath tumors (MPNSTs) with a combination of inhibitors. The most effective therapy is to combine an inhibitor of TYK2 with a MEK inhibitor.
MPNST…
by | Jun 2, 2022 | Guan, Jianjun, Guan, Ya, Niu, Hong
— Technology Description
Researchers in Jianjun Guan’s lab at Washington University have developed an oxygen-releasing hydrogel that accelerates wound healing. The biodegradable hydrogel is loaded with oxygen release microspheres (ORM) that slowly release oxygen into the surrounding tissue to …
by | Jan 29, 2021 | Mitra, Robi, Moudgil, Arnav, Wilkinson, Michael Nathaniel
— Technology Description
Researchers in Robi Mitra’s lab at Washington University in St. Louis have developed a method to increase the sensitivity of leukemias to chemotherapy by pre-treatment with a BET inhibitor. BET inhibitors convert stem-like leukemia cells to a more differentiated state …