by | Aug 10, 2023 | Jha, Abhinav Kumar, Li, Ran, Woodard, Pamela, Zheng, Jie
— Technology Description
Researchers at Washington University in St. Louis have developed a two-stage neural network model, with CNN and BNN architecture, to segment carotid atherosclerotic plaque components based on multi-weighted MR images and measure the uncertainty of the segmentation output. Th…
by | Jun 28, 2022 | Carrasquel Ursulaez, Willy, Chanda, Baron
— Technology Description
Researchers in Baron Chanda’s lab at Washington University and Jennifer Schomaker’s lab at University of Wisconsin-Madison have developed a library of benzo(crown-ether) compounds capable of self-assembly into ion channels. These monoacylated and monoalkylated be…
by | Mar 2, 2022 | Lim, Kian-Huat, Liu, Yongjian, Zhang, Xiaohui
— Disease indication –
Drug format – Combination containing radiolabeled copper nanocluster, small molecule, and peptide
Drug class – First-in-class
Target – CCR2, the receptor for CCL2
Mode of action – The ECL1i peptide is conjugated to a copper nanocluster loaded…
by | Feb 18, 2022 | Mudd, Philip
— Technology Description
Researchers in Philip Mudd’s lab at Washington University have developed a blood biomarker test that detects impending respiratory failure before existing diagnostics. High levels of the biomarker IP-10 in the blood are correlated with the subsequent development of acu…
by | Jan 12, 2021 | Amarasinghe, Gaya
— Ebola viral protein 30 (eVP30) plays a critical role in transcription initiation for viral RNA synthesis. These materials could be used to test for Ebola virus infection.
Publication: Xu, W., Luthra, P., Wu, C., Batra, J., Leung, D. W., Basler, C. F., & Amarasinghe, G. K. (2017). Ebola virus VP…