by | May 5, 2020 | Mach, Robert, Tu, Zhude "Will", Wang, Wei
— Technology Description
Researchers at Washington University in St. Louis and their colleagues have developed positron emission tomography (PET) tracers with high affinity for sigma-1 receptors. Sigma receptors have two subtypes, sigma-1 and sigma-2. Sigma-1 has high expression in the limbic and mo…
by | Feb 27, 2020 | Green, Olga, Mutic, Sasa, Park, Chunjoo (Justin), Zhang, Hao
— Technology Description
A team of researchers at Washington University School of Medicine developed deep learning image processing techniques to improve MRI diagnostics and potentially enable faster, more precise MRI-guided radiation therapy without exposing patients to radiation from CT imaging. S…
by | Nov 18, 2019 | Altman, Michael, Green, Olga, Kavanaugh, James, Li, Hua, Mutic, Sasa, Wooten, Hasani
— Technology Description
A team of researchers at Washington University has created a machine learning method to quickly and reliably validate patient contours in digital medical images for radiation therapy and computer aided image analysis.
Currently, automated contouring tools for delineating tu…
by | Mar 10, 2018 | Achilefu, Samuel, Black, Kvar
— This invention is the formulation of a SPECT nanoparticle probe for the detection of MMP activity. The surface of a 10 nm-sized gold nanoparticle is functionalized through a thiol anchor with a peptide that is cleaved in the presence of MMP9. The surface is also functionalized with methoxy polyethyl…
by | Mar 10, 2018 | Achilefu, Samuel, Berezin, Mikhail, Zhang, Zongren
— Background: Near Infrared (NIR) fluorescence can be highly useful in biological systems as it is highly sensitive and allows for detection and imaging of physiological and molecular processes in cells and living organisms. However, radiometric imaging is difficult in the NIR region of the light spec…