by | Apr 28, 2025 | Apte, Rajendra, Yoshino, Jun
— Published Date: 4/29/2025
Value Proposition: Novel biomarker that can be used as a diagnostic to identify glaucoma severity or progression in patients.
Technology Description
Researchers at Washington University in St. Louis have identified a novel biomarker, GDF15, for glaucoma that can detect …
by | Jul 27, 2020 | Apte, Rajendra, Van Stavern, Gregory
— Technology Description
Researchers at Washington University in St. Louis have developed a non-invasive screening method using optical coherence tomography angiography (OCTA) to detect Alzheimer’s disease (AD) at the early, preclinical stage. AD is characterized by progressive memory loss, be…
by | Dec 1, 2019 | Covey, Douglas, Izumi, Yukitoshi, Zorumski, Charles
— Technology Description
Researchers from Washington University in St. Louis and colleagues have identified ent-allopregnanolone (ent-AlloP) as a potential therapeutic to treat glaucoma. Glaucoma, the leading cause of irreversible blindness, results from damage to the retinal ganglion cells (RGSs) t…
by | Oct 22, 2019 | Blumer, Kendall, Onken, Michael
— Disease indication – Uveal melanoma and other G protein-driven disorders, including other cancers (certain vascular tumors, colon, lung, adenocarcinoma, skin melanoma, thyroid adenoma), cholera and Sturge-Weber Syndrome
Drug format – small molecule (FR900359, a bioavailable inhibitor of…
by | Oct 22, 2019 | Apte, Rajendra
— Technology Description
Researchers in Prof. Rajendra Apte’s laboratory developed novel methods for treating macular degeneration and other eye diseases by targeting a cholesterol transport pathway involved in the formation of new blood vessels. Age-related macular degeneration (AMD) is a lea…