by | Dec 1, 2019 | Covey, Douglas, Izumi, Yukitoshi, Zorumski, Charles
— Technology Description
Researchers from Washington University in St. Louis and colleagues have identified ent-allopregnanolone (ent-AlloP) as a potential therapeutic to treat glaucoma. Glaucoma, the leading cause of irreversible blindness, results from damage to the retinal ganglion cells (RGSs) t…
by | Oct 22, 2019 | Mennerick, Steven, Sun, Min-Yu, Taylor, Amanda, Zorumski, Charles
— Disease indication – neuroprotection in stroke/ischemia with potential for treating other neurodegenerative diseases
Drug format – neurosteroid
Drug class – drug repurposing (25-hydroxycholesterol)
Research stage and Preliminary data:
In vitro – The inventors demonstrated…