by | Jun 11, 2021 | Shen, Hua
— Technology Description:
A team of researchers at Washington University has developed a cell-free, nano-sized extracellular vesicle (EV/exosome) system to enhance repair of soft musculoskeletal tissue. This technology leverages the natural anti-inflammatory effects of adipose-derived stem cells (ASC…
by | Apr 26, 2021 | Hawasli, Ammar, Jayasekera, Dinal, Lamichhane, Bidhan, Leuthardt, Eric, Ray, Wilson
— Technology Description:
Researchers at Washington University, led by Eric Leuthardt, have developed software that can identify specific brain regions involved in chronic low back pain from neuroimaging data. This software, powered by machine learning, relies on differences in cortical thickness an…
by | Jan 20, 2021 | Barcellona, Marcos, Setton, Lori, Speer, Julie
— Background:
Severe low back pain and disability can result from intervertebral disc (IVD) degeneration caused by cell phenotype changes in the nucleus pulposus (NP) region. While autologous stem cells have be used to treat lower back pain, currently there are no tools to control differentiation of…
by | Dec 11, 2020 | Luhmann, Scott
— Technology Description:
Researchers at Washington University in St. Louis have identified blood-based cytokine signatures that could be used to specifically detect, distinguish and monitor septic arthritis, synovitis and osteomyelitis. This assay could enable timely, accurate treatment to avoid joi…
by | Apr 8, 2020 | Genin, Guy, Linderman, Stephen, Thomopoulos, Stavros
— Technology Description
An interdisciplinary team at Washington University in St. Louis has developed patented adhesive-coated sutures with the potential to reduce ruptures following surgical repair of tendons and ligaments. These modified sutures are designed to minimize stress by shifting the mec…