by | Dec 19, 2024 | Chou, Chun, Egawa, Takeshi
— Published Date: 12/19/2024
Value Proposition: This invention utilizes a protein to enhance T cell expansion for CAR-T cell therapy and other adoptive cellular immunotherapy.
Technology Description
Researchers at Washinton University in St. Louis have developed a mutant AP4 protein that is desig…
by | Dec 18, 2024 | Klechevsky, Eynav, Pathak, Amit, Sarker, Bapi
— Published Date: 12/19/2024
Value Proposition: New method for expanding T cells against individualized tumor-specific mutational antigens.
Technology Description
Researchers at Washington University in St. Louis have developed a device that enables high-throughput production of patient specific …
by | Jun 28, 2022 | Klein, Robyn, Williams, Jessica
— Technology Description
Researchers in Prof. Robyn Klein’s laboratory have discovered that interferon lambda (IFN-λ) is a potential target for treating multiple sclerosis (MS), particularly secondary progressive MS (SPMS).
Most patients with MS present with relapsing remitting MS (RRM…
by | Jun 2, 2022 | Guan, Jianjun, Guan, Ya, Niu, Hong
— Technology Description
Researchers in Jianjun Guan’s lab at Washington University have developed an oxygen-releasing hydrogel that accelerates wound healing. The biodegradable hydrogel is loaded with oxygen release microspheres (ORM) that slowly release oxygen into the surrounding tissue to …
by | Apr 27, 2022 | Chang, Ju Fang, Singh, Nathan
— Technology Description
Researchers in Nathan Singh’s lab at Washington University have developed a construct for cell therapy that combines facets of existing CAR-T therapy and the endogenous T cell receptor (TCR) to better regulate adoptive cell activation. Unlike the traditional TCR, this …