by | Apr 26, 2021 | Chapman Jr., William "Will Jr", Leng, Xiandong, Mutch, Matthew, Uddin, Shihab, Zhu, Quing
— Technology Description:
Researchers led by Quing Zhu at Washington University have developed a method for imaging rectal tumors using photoacoustic microscopy and ultrasound with a machine learning component. This method is better able to differentiate residual cancer from healthy tissue following…
by | Sep 21, 2020 | Kaiko, Gerard, Liu, Ta-Chiang, Stappenbeck, Thaddeus
— Plasminogen activator inhibitor-1 (PAI-1) has been identified as a specific biomarker that is significantly elevated in patients with inflammatory bowel disease (IBD) and is correlated with disease severity. It could be used to both diagnose the disease (including ulcerative colitis and colonic Croh…
by | May 18, 2020 | Stappenbeck, Thaddeus, VanDussen, Kelli
— Technology Description
Researchers in the Stappenbeck lab have discovered an objective histologic biomarker on intestinal cells that can predict a patient’s response to ustekinumab treatment for Crohn’s disease or ulcerative colitis. Specifically, the length of microvilli (MV) could pr…
by | May 11, 2020 | Gordon, Jeffrey, Patnode, Michael
— Technology Description
Researchers at Washington University in St. Louis have developed a bead-based method to understand the functional states and metabolic capabilities of individual members of the human gut microbiota. The gut microbiota is increasingly linked to multiple aspects of human healt…
by | May 11, 2020 | Gordon, Jeffrey, Raman, Arjun
— Technology Description
Researchers at Washington University in St. Louis have developed a method to stratify gut microbiota dysbiosis and monitor treatments to correct it. In order to efficiently treat microbiota imbalance, it would first be beneficial to understand the healthy organization and in…