— Technology Description
Researchers at Washington University in St. Louis have developed a 3D-printed device for the subcutaneous transplantation of stem cell-derived beta (SC-beta) cells for diabetes cell replacement therapy. Diabetes mellitus, a disease characterized by loss of blood glucose cont…
— Technology Description
Researchers at Washington University in St. Louis have developed an improved method to differentiate stem-cells into functionally mature, insulin-secreting beta cells (SC-beta cells). Pancreatic beta cells play an important role in controlling blood glucose levels as they se…
— Disease indication: metabolic disorders including insulin resistance and diabetic nephropathy
Drug format: chemically modified synthetic microRNA (miRNA)
Drug class: first-in-class for metabolic disease
Research stage and Preliminary data:
Target: miR-29 mimics can increase the gene expressio…
— Background
Over 30% of adults in the world are overweight or obese. Lifestyle management has proven to be impractical and ineffective in real-life settings and there are no current treatments available for metabolic disease.
Technology Summary
Pharmacological or genetic activation of the Arginine…
— Background
Over 30% of adults in the world are overweight or obese. Lifestyle management has proven to be impractical and ineffective in real-life settings and there are no current treatments available for metabolic disease.
Technology Summary
Pharmacological or genetic activation of the Arginine…
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Creating...
