by | Oct 18, 2022 | Semenkovich, Clay, Zayed, Mohamed
— Technology Description
Researchers from Mohamed Zayed’s lab at Washington University have developed a blood biomarker test for atherosclerosis more accurate than LDL. Circulating levels of Fatty Acid Synthase (cFAS) in the serum correlate to a high degree to severity of peripheral atheroscle…
by | Jul 1, 2022 | Shenoy, Surendra
— Technology Description
Researchers at Washington University in St. Louis have developed a technique for arteriovenous fistula creation that reduces the incidence of juxta-anastomotic stenosis, which often leads to graft failure. The procedure involves clamping closed one end of the graft and attac…
by | Jun 8, 2022 | Wirtz, Alexander, Zayed, Mohamed
— Technology Description
Researchers at Washington University in St. Louis developed an improved stent system to treat aorto-iliac occlusive disease. Aorto-iliac occlusive disease is caused by atherosclerotic plaque accumulation in the abdominal aorta where it connects to the common iliac arteries. …
by | Feb 23, 2022 | Cui, Jianmin
— Disease indication – Long QT Syndrome (resulting in ventricular arrhythmia, epilepsy, deafness)
Drug format – Small molecule
Drug class – Lead compounds are repurposed drugs
Research stage and preliminary data – Based on in silico screening of KCNQ, the researchers selecte…
by | Jan 20, 2022 | Bayly, Philip, Derdeyn, Colin, Elbert, Donald, Genin, Guy, Leuthardt, Eric, McCoy, Kathleen, Suh, JunWoo, Teh, Yuni, Vemuri, Chandu, Zhao, Alan, Zipfel, Gregory
— Background: Popliteal artery aneurysms are the most prevalent type of peripheral aneurysms and are treated surgically to prevent rupture. Currently, surgical options include open surgery or endovascular aneurysm repair (EVAR). EVAR is less invasive than open surgery, resulting in shorter hospital st…