by | Oct 18, 2022 | Genin, Guy, Williams, Dillon, Zayed, Mohamed
— Technology Description
Prof. Mohamed Zayed and colleagues have developed an arteriovenous graft cuff with features designed to normalize the blood shear rate and decrease risk of thrombosis at the venous end anastomosis. This device could reduce the failure rate of these grafts, thereby improving …
by | Oct 18, 2022 | Semenkovich, Clay, Zayed, Mohamed
— Technology Description
Researchers from Mohamed Zayed’s lab at Washington University have developed a blood biomarker test for atherosclerosis more accurate than LDL. Circulating levels of Fatty Acid Synthase (cFAS) in the serum correlate to a high degree to severity of peripheral atheroscle…
by | Jul 1, 2022 | Shenoy, Surendra
— Technology Description
Researchers at Washington University in St. Louis have developed a technique for arteriovenous fistula creation that reduces the incidence of juxta-anastomotic stenosis, which often leads to graft failure. The procedure involves clamping closed one end of the graft and attac…
by | Jun 8, 2022 | Wirtz, Alexander, Zayed, Mohamed
— Technology Description
Researchers at Washington University in St. Louis developed an improved stent system to treat aorto-iliac occlusive disease. Aorto-iliac occlusive disease is caused by atherosclerotic plaque accumulation in the abdominal aorta where it connects to the common iliac arteries. …
by | Feb 23, 2022 | Cui, Jianmin
— Disease indication – Long QT Syndrome (resulting in ventricular arrhythmia, epilepsy, deafness)
Drug format – Small molecule
Drug class – Lead compounds are repurposed drugs
Research stage and preliminary data – Based on in silico screening of KCNQ, the researchers selecte…