Small molecules targeting KCNQ in ventricular arrhythmia

— Disease indication – Long QT Syndrome (resulting in ventricular arrhythmia, epilepsy, deafness)

Drug format – Small molecule

Drug class – Lead compounds are repurposed drugs

Research stage and preliminary data – Based on in silico screening of KCNQ, the researchers selecte…

SPARTA – A Stent for Fusiform Aneurysms that Prevents Endoleaks

— Background: Popliteal artery aneurysms are the most prevalent type of peripheral aneurysms and are treated surgically to prevent rupture. Currently, surgical options include open surgery or endovascular aneurysm repair (EVAR). EVAR is less invasive than open surgery, resulting in shorter hospital st…

String Theory: Neurovascular Catheter System with 2-in-1 Variable Rigidity

— An interdisciplinary team at Washington University has developed an easy-to-use neurovascular catheter system designed to reduce surgery time and prevent herniation during transradial interventions for stroke, aneurysms and other conditions. This device, called “String Theory”, can be sw…

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