by | Mar 27, 2018 | Song, Sheng-Kwei "Victor", Wang, Qing, Wang, Yong
— Background: Diffusion tensor imaging (DTI) has demonstrated sensitivity to detect pathologies in CNS white matter disorders. However, the capability of DTI to detect CNS white matter pathologies is confounded by the coexisting structural (crossing fibers) and pathological (inflammation associated ce…
by | Mar 10, 2018 | Achilefu, Samuel, Berezin, Mikhail, Zhang, Zongren
— Background: Near Infrared (NIR) fluorescence can be highly useful in biological systems as it is highly sensitive and allows for detection and imaging of physiological and molecular processes in cells and living organisms. However, radiometric imaging is difficult in the NIR region of the light spec…
by | Mar 10, 2018 | Rossin, Raffaella, Welch, Michael, Woodard, Pamela
— Background
Atherosclerosis is a disease process in which lipid deposition causes the formation of plaques that lead to thickening of the artery walls. The cause of a majority of fatal acute myocardial infarction and sudden coronary death is due to the rupture of soft or unstable plaques; however, t…
by | Mar 10, 2018 | Li, Li, Wang, Lihong
— Optical coherence tomography (OCT) utilizes optical light to obtain an image of opaque or translucent objects, ie tissue. Because scattered light contributes to the bluring found in other optical imaging techniques, OCT filters out all the scattered light. An image is formed using only the back refl…
by | Mar 10, 2018 | Maslov, Konstantin, Rao, Bin, Wang, Lihong
— A photoacoustic tomography device that provides high optical absorption contrast with high lateral resolution, including very good melanin distribution images, for port wine stain birthmarks.