Small molecules targeting KCNQ in ventricular arrhythmia

— Disease indication – Long QT Syndrome (resulting in ventricular arrhythmia, epilepsy, deafness)

Drug format – Small molecule

Drug class – Lead compounds are repurposed drugs

Research stage and preliminary data – Based on in silico screening of KCNQ, the researchers selecte…

Controlling charge doping in 2D materials

— Technology Description

Researchers at Washington University in St. Louis have developed a method to control charge doping in 2D materials like graphene. This method uses α-RuCl3 to create pn junctions at a smaller scale than silicon transistors.

While α-RuCl3 efficiently removes el…

SPARTA – A Stent for Fusiform Aneurysms that Prevents Endoleaks

— Background: Popliteal artery aneurysms are the most prevalent type of peripheral aneurysms and are treated surgically to prevent rupture. Currently, surgical options include open surgery or endovascular aneurysm repair (EVAR). EVAR is less invasive than open surgery, resulting in shorter hospital st…

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