In vivo editing via targeted adenoviral vectors

— Background:

Viral vectors have been used for in vivo delivery of CRISPR/Cas9. However, it’s applications have been limited by the native tropism of the viral vector. To better utilize in vivo editing, methods must be developed to accomplish efficient, selective and coordinated delivery of CRI…

Novel Acute Myocardial Injury Biomarker Profile

— Background: Cardiovascular disease, including acute myocardial injury (AMI), is responsible for over 610,000 deaths per year in the US making it the number one cause of death. The gold standard for AMI diagnosis relies on determination of the cardiac troponin I (cTnI) plasma level. The rise in the l…

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