by | Apr 26, 2021 | Hawasli, Ammar, Jayasekera, Dinal, Lamichhane, Bidhan, Leuthardt, Eric, Ray, Wilson
— Technology Description:
Researchers at Washington University, led by Eric Leuthardt, have developed software that can identify specific brain regions involved in chronic low back pain from neuroimaging data. This software, powered by machine learning, relies on differences in cortical thickness an…
by | Mar 1, 2021 | Li, Jr-Shin, Zlotnik, Anatoly
— Technology Description:
Researchers in Prof. Jr-Shin Li’s laboratory have developed a robust, scalable, patented technology to control and entrain complex, noisy, non-linear oscillating systems such as neuronal firing and circadian rhythms. This system uses a single global, open-loop control …
by | Sep 24, 2020 | Song, Sheng-Kwei "Victor", Ye, Zezhong
— Researchers in Prof. Sheng-Kwei (Victor) Song’s laboratory have developed diffusion histology imaging (“DHI”), a tool to provide a non-invasive diagnosis for accurately grading tumors and guiding treatment decisions. This “virtual histopathology” technology classifies mic…
by | Sep 3, 2020 | Curiel, David
— Background:
Viral vectors have been used for in vivo delivery of CRISPR/Cas9. However, it’s applications have been limited by the native tropism of the viral vector. To better utilize in vivo editing, methods must be developed to accomplish efficient, selective and coordinated delivery of CRI…
by | Sep 3, 2020 | Hu, Yifei, Van Dyke-Blodgett, Joshua
— Background:
Compounds containing piperazic acid (Piz), a nonproteinogenic amino acid, are of significant interest for drug discovery. Peptidic compounds incorporating Piz as a building block include antibacterial, antiviral, immunomodulatory and anticancer drug leads, and all naturally-occurring Pi…