by | Sep 3, 2020 | Hu, Yifei, Van Dyke-Blodgett, Joshua
— Background:
Compounds containing piperazic acid (Piz), a nonproteinogenic amino acid, are of significant interest for drug discovery. Peptidic compounds incorporating Piz as a building block include antibacterial, antiviral, immunomodulatory and anticancer drug leads, and all naturally-occurring Pi…
by | Apr 29, 2020 | Bach, Richard, Boyle, Walter
— Background: Cardiovascular disease, including acute myocardial injury (AMI), is responsible for over 610,000 deaths per year in the US making it the number one cause of death. The gold standard for AMI diagnosis relies on determination of the cardiac troponin I (cTnI) plasma level. The rise in the l…
by | Mar 5, 2020 | Chung, Charles, Kovacs, Sandor, Shmuylovich, Leonid, Zhang, Weixiong
— Technology Description
Researchers in the Cardiovascular Biophysics Laboratory at Washington University developed a patented, real-time, automated index to reliably detect delayed relaxation during cardiac catheterization diagnostics. This technique, called pressure recovery ratio (PRR), serves as…
by | Mar 5, 2020 | Chung, Charles, Kovacs, Sandor, Shmuylovich, Leonid, Zhang, Weixiong
— Technology Description
Researchers in the Cardiovascular Biophysics Laboratory at Washington University developed a patented, real-time, automated index to reliably detect delayed relaxation during cardiac catheterization diagnostics. This technique, called pressure recovery ratio (PRR), serves as…
by | Feb 27, 2020 | Green, Olga, Mutic, Sasa, Park, Chunjoo (Justin), Zhang, Hao
— Technology Description
A team of researchers at Washington University School of Medicine developed deep learning image processing techniques to improve MRI diagnostics and potentially enable faster, more precise MRI-guided radiation therapy without exposing patients to radiation from CT imaging. S…