Small molecules targeting KCNQ in ventricular arrhythmia

— Disease indication – Long QT Syndrome (resulting in ventricular arrhythmia, epilepsy, deafness)

Drug format – Small molecule

Drug class – Lead compounds are repurposed drugs

Research stage and preliminary data – Based on in silico screening of KCNQ, the researchers selecte…

Photothermal disinfection of N95 respirators

— Technology Description

A team of researchers led by Young-Shin Jun have developed a polymer coating for N95 respirators that would permit fast, easy, and cheap N95 disinfection using only direct sunlight. The researchers coated the outermost fabric layer in polydopamine, which converts photon energ…

In vivo editing via targeted adenoviral vectors

— Background:

Viral vectors have been used for in vivo delivery of CRISPR/Cas9. However, it’s applications have been limited by the native tropism of the viral vector. To better utilize in vivo editing, methods must be developed to accomplish efficient, selective and coordinated delivery of CRI…

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