by | Jul 10, 2023 | Hatoum, Alexander
— Technology Description
Researchers at Washington University in St. Louis, led by Dr. Alexander Hatoum, have developed a computational model for improving the diagnosis and treatment of drug addiction. Using genome-wide association study (GWAS) of over 1 million subjects, Dr. Hatoum’s group d…
by | Jan 20, 2023 | Oh, Youngmi, Yoo, Andrew
— Technology Description
Researchers in Andrew Yoo’s laboratory at Washington University have developed an antisense oligonucleotide targeting a miRNA (miR-29b-3p) as a treatment for Huntington’s disease (HD). Inhibiting miR-29b-3p promotes neuronal survival by rescuing neurons from deg…
by | Jul 26, 2022 | Amin, Neha, Borcherding, Dana, Hirbe, Angela
— Technology Description
Researchers in Angela Hirbe’s lab at Washington University have developed a method of treating malignant peripheral nerve sheath tumors (MPNSTs) with a combination of inhibitors. The most effective therapy is to combine an inhibitor of TYK2 with a MEK inhibitor.
MPNST…
by | Jul 1, 2022 | Shenoy, Surendra
— Technology Description
Researchers at Washington University in St. Louis have developed a technique for arteriovenous fistula creation that reduces the incidence of juxta-anastomotic stenosis, which often leads to graft failure. The procedure involves clamping closed one end of the graft and attac…
by | Jun 28, 2022 | Klein, Robyn, Williams, Jessica
— Technology Description
Researchers in Prof. Robyn Klein’s laboratory have discovered that interferon lambda (IFN-λ) is a potential target for treating multiple sclerosis (MS), particularly secondary progressive MS (SPMS).
Most patients with MS present with relapsing remitting MS (RRM…