by | Jan 5, 2026 | Dai, Yifan, Pappu, Rohit
— Published date: 1/6/2025
Value Proposition: Directed evolution of synthetic intrinsically disordered proteins for condensate editing.
Technology Description
Researchers at Washington University in St. Louis have developed a directed evolution method and selection strategies to enable the evolut…
by | Sep 17, 2025 | Fremont, Daved, Nelson, Christopher, Teitelbaum, Steven, Warren, Julia
— Published date: 9/18/2025
Value Proposition: Single chain RANK ligand that can selectively inhibit pathological bone loss.
Technology Description
Researchers at Washington University in St. Louis have developed a genetically engineered mutant RANKL protein that prevents bone loss by selective…
by | Jun 3, 2025 | Feldman, Mario, Jana, Biswanath, Pardue, Evan, Sartorio, Mariana
— Published Date: 6/3/2025
Value Proposition: System that employs gut microbe strains engineered with therapeutic enzymes to treat chronic gut conditions.
Technology Description
Researchers at Washington University in St. Louis have developed a hypervesiculating Bacteroides theatiotaomicron (Bt) …
by | May 14, 2025 | DiPersio, John, Ghobadi, Armin, O'Neal, Julie, Ritchey, Julie
— Published Date: 5/13/2025
Value Proposition: An innovative therapy leveraging unique chimeric antigen receptors (CAR) to specifically target Fc receptor-like 5 (FCRL5), enabling the precise elimination of FCRL5-expressing cells to treat multiple myeloma and other cancers.
Technology Description
…
by | May 14, 2025 | Oh, Youngmi, Yoo, Andrew
— Published Date: 5/14/2025
Value Proposition: Novel antisense oligonucleotide (ASO) directly targeting a microRNA-mediated mechanism responsible for autophagy reduction and neurodegeneration in Huntington’s disease (HD) improving patient outcomes in pre-HD subjects.
Technology Description
R…