by | Jul 21, 2026 | Ma, Liang, Yin, Yan
— Published date: 7/22/2026
Value Proposition: New process that tackles two RA signaling pathways to improve treatment of various diseases.
Technology Description
Researchers at Washington University in St. Louis have uncovered an antagonistic interaction between estrogen and retinoic acid (RA) …
by | Jan 5, 2026 | Dai, Yifan, Pappu, Rohit
— Published date: 1/6/2025
Value Proposition: Directed evolution of synthetic intrinsically disordered proteins for condensate editing.
Technology Description
Researchers at Washington University in St. Louis have developed a directed evolution method and selection strategies to enable the evolut…
by | May 13, 2025 | Djuranovic, Sergej, Pirzada, Mujeeb
— Published Date: 5/14/2025
Value proposition: Novel ASOs that increase key protein production to limit neurodegeneration caused by ALS and frontotemporal dementia (FTD).
Technology Description
TDP-43 pathology is present in ~97% of ALS, ~50% of FTD, and frequently observed in other neurodegenerat…
by | May 13, 2025 | Cavalli, Valeria, Feng, Rui
— Published Date: 12/21/24
Value proposition: A cost-effective, drug-based therapy targeting the endothelin B receptor (ETBR) to promote peripheral nerve regeneration, offering improved recovery and compatibility with existing treatments.
Technology Description
Researchers at Washington University…
by | Jan 8, 2025 | Dantas, Gautam, Gorushi, Olivia, Helmink, Beth, Kwak, Suryang, Prusa, Jerome, Wallace, Miranda
— Published date: 1/9/2025
Value Proposition: Genetically engineered yeast used to treat gastrointestinal tumors through the delivery of immune checkpoint inhibitor (ICI) proteins.
Technology Description
Researchers at Washington University in St. Louis have developed a genetically engineered …