by | Dec 18, 2024 | Klechevsky, Eynav, Pathak, Amit, Sarker, Bapi
— Published Date: 12/19/2024
Value Proposition: New method for expanding T cells against individualized tumor-specific mutational antigens.
Technology Description
Researchers at Washington University in St. Louis have developed a device that enables high-throughput production of patient specific …
by | Jun 2, 2022 | Guan, Jianjun, Guan, Ya, Niu, Hong
— Technology Description
Researchers in Jianjun Guan’s lab at Washington University have developed an oxygen-releasing hydrogel that accelerates wound healing. The biodegradable hydrogel is loaded with oxygen release microspheres (ORM) that slowly release oxygen into the surrounding tissue to …
by | Mar 2, 2022 | Lim, Kian-Huat, Liu, Yongjian, Zhang, Xiaohui
— Disease indication –
Drug format – Combination containing radiolabeled copper nanocluster, small molecule, and peptide
Drug class – First-in-class
Target – CCR2, the receptor for CCL2
Mode of action – The ECL1i peptide is conjugated to a copper nanocluster loaded…
by | Feb 16, 2022 | Azab, Abdel Kareem, Federico, Cinzia
— Technology Description
Researchers in Prof. Kareem Azab’s laboratory have developed a liposome drug delivery vehicle to improve efficacy and reduce side effects of multiple myeloma treatment. This system is designed to target compounds to the bone marrow microenvironment (BMME) and simultane…
by | Feb 16, 2022 | Azab, Abdel Kareem, Muz, Barbara
— Researchers in Prof. Abdel Kareem Azab’s laboratory have developed a biologically-targeted cellular drug delivery system to precisely target therapeutic or diagnostic agents to a wide range of cancers. Delivering drugs directly to cancer cells and not to healthy cells could improve outcomes by…