by | May 28, 2020 | Guruswami, Sundaram, Sharma, Vijay, Sivapackiam, Jothilingam
— Technology Description
Researchers at Washington University in St. Louis have developed PET radiotracers to image amyloid beta (A-beta) at early stages of Alzheimer’s Disease (AD). For AD treatment to be effective, it may have to be administered during the preclinical stage. As such, there i…
by | May 18, 2020 | Stappenbeck, Thaddeus, VanDussen, Kelli
— Technology Description
Researchers in the Stappenbeck lab have discovered an objective histologic biomarker on intestinal cells that can predict a patient’s response to ustekinumab treatment for Crohn’s disease or ulcerative colitis. Specifically, the length of microvilli (MV) could pr…
by | Apr 29, 2020 | Bach, Richard, Boyle, Walter
— Background: Cardiovascular disease, including acute myocardial injury (AMI), is responsible for over 610,000 deaths per year in the US making it the number one cause of death. The gold standard for AMI diagnosis relies on determination of the cardiac troponin I (cTnI) plasma level. The rise in the l…
by | Apr 27, 2020 | Cruchaga, Carlos, Dube, Umber, Ibanez, Laura
— Technology Description:
Researchers in Prof. Carlos Cruchaga’s laboratory have identified a sensitive and specific panel of circular RNAs (circRNA) that could be used for diagnosing, screening or monitoring patients with Alzheimer’s disease. The expression of these circRNAs tracks with …
by | Apr 6, 2020 | Storch, Gregory, Wylie, Kristine, Wylie, Todd
— Technology Description
A team of researchers at Washington University developed “ViroCap”, a patented capture probe technique for senistive, comprehensive, in-depth metagenomics analysis vertebrate viruses. This invention could enhance traditional metagenomics shotgun sequencing (MSS) w…