by | Oct 22, 2019 | Dhavale, Dhruva, Kotzbauer, Paul, Tu, Zhude "Will", Yue, Xuyi
— Technology Description
A team of researchers at Washington University have developed and optimized highly potent PET imaging probes which are specific for the misfolded protein that is the hallmark of Parkinson’s disease and related disorders. This family of molecules was designed based on s…
by | Oct 22, 2019 | Crimmins, Dan, Gaut, Joseph, Ladenson, Jack, Laterza, Omar, Lockwood, Christina, Modur, Vijay
— Technology Description
A team of researchers at Washington University in St. Louis have developed patented antibodies designed to identify MIOX (myo-inositol oxygenase), a renal-specific biomarker that can be detected immediately following acute kidney injury (AKI). AKI can be caused by surgery, s…
by | Oct 22, 2019 | Kharasch, Evan, Morrissey, Jeremiah, Singamaneni, Srikanth, Tadepalli, Sirimuvva
— Technology Description
An interdisciplinary team of researchers at Washington University have developed a sensitive, shelf-stable, label-free system for quickly quantifying biomarkers in point-of-care settings (e.g., office, ambulance or battlefield). Localized surface plasmon resonance (LSPR) off…
by | Oct 22, 2019 | Xu, Mai
— Background: In the US alone, 154,000 new cases of colorectal cancer (CRC) are diagnosed each year. Unfortunately, a third of those patients will die due to diagnosis at late stages – the 5-year survival rate is 11%, compared to 91% for those who are diagnosed with only localized CRC. A colonos…
by | Oct 22, 2019 | Cupps, Brian, Pasque, Michael
— Background: Assessing left ventricle (LV) cardiac contractile function is a good indicator of overall heart health and is used to determine which patients are good candidates for revascularization surgery. With over 3 million new coronary artery disease patients annually and over 1 million annual re…