by | May 14, 2025 | Oh, Youngmi, Yoo, Andrew
— Published Date: 5/14/2025
Value Proposition: Novel antisense oligonucleotide (ASO) directly targeting a microRNA-mediated mechanism responsible for autophagy reduction and neurodegeneration in Huntington’s disease (HD) improving patient outcomes in pre-HD subjects.
Technology Description
R…
by | May 14, 2025 | DiPersio, John, Ghobadi, Armin, O'Neal, Julie, Ritchey, Julie
— Published Date: 5/13/2025
Value Proposition: An innovative therapy leveraging unique chimeric antigen receptors (CAR) to specifically target Fc receptor-like 5 (FCRL5), enabling the precise elimination of FCRL5-expressing cells to treat multiple myeloma and other cancers.
Technology Description
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by | Apr 28, 2025 | Apte, Rajendra, Yoshino, Jun
— Published Date: 4/29/2025
Value Proposition: Novel biomarker that can be used as a diagnostic to identify glaucoma severity or progression in patients.
Technology Description
Researchers at Washington University in St. Louis have identified a novel biomarker, GDF15, for glaucoma that can detect …
by | Dec 19, 2024 | Chou, Chun, Egawa, Takeshi
— Published Date: 12/19/2024
Value Proposition: This invention utilizes a protein to enhance T cell expansion for CAR-T cell therapy and other adoptive cellular immunotherapy.
Technology Description
Researchers at Washinton University in St. Louis have developed a mutant AP4 protein that is desig…
by | Dec 18, 2024 | Klechevsky, Eynav, Pathak, Amit, Sarker, Bapi
— Published Date: 12/19/2024
Value Proposition: New method for expanding T cells against individualized tumor-specific mutational antigens.
Technology Description
Researchers at Washington University in St. Louis have developed a device that enables high-throughput production of patient specific …