by | Mar 10, 2018 | Mach, Robert, Rowland, Douglas, Tu, Zhude "Will", Welch, Michael
— The sigma-2 (σ2) receptor is an important target for the development of molecular probes in oncology because of its 10-fold higher density in proliferating tumor cells than in quiescent tumor cells, and the observation that σ2 receptor agonists are able to kill tumor cells via apoptotic …
by | Mar 10, 2018 | Corbo, Joseph, Havranek, James, Mitra, Robi, Myers, Connie, Qi, Zongtai, Zhang, Chi
— Background: The function of enzymes involved in homologous recombination can be exploited in the field of genetic engineering in order to generate mutations of interest. However, this machinery is not functionally efficient in post mitotic or terminally differentiated cells. Viral gene therapy techn…
