— Value Proposition: Small molecule Gastrin-releasing peptide receptor (GRPR) antagonists used to treat chronic itch.
Technology Description
Researchers at Washington University in St. Louis have discovered a group of small molecule Gastrin-releasing peptide receptor (GRPR) antagonists to treat c…
— T-020153 – Small Molecule Agonists of EphA Receptors to Ameliorate Diabetes
Technology Description
Blood glucose levels (left), post-treatment plasma glucagon (center) in WCDD301 treated NOD (non-obese diabetic) mice with moderate hyperglycemia. Blood glucose levels (right) in Streptozotocin-ind…
— Disease indication – Diseases related to oxidative stress, including cancer, autoimmune disease, and Toxoplasma infection
Drug format – Small molecule
Drug class – Best-in-class
Research stage and preliminary data – The researchers have synthesized a series of pyrimethamin…
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