by | Dec 19, 2024 | Chheda, Milan, Curiel, David, Diamond, Michael, Li, Yuping
— Published Date: 12/20/2024
Value Proposition: Treats brain tumors by combining a hematopoietic growth protein and cancer therapeutics to increase survival rates.
Technology Description
Researchers at Washington University in St. Louis have developed a new way to treat brain cancers by combining…
by | Sep 3, 2020 | Curiel, David
— Background:
Viral vectors have been used for in vivo delivery of CRISPR/Cas9. However, it’s applications have been limited by the native tropism of the viral vector. To better utilize in vivo editing, methods must be developed to accomplish efficient, selective and coordinated delivery of CRI…
by | Jun 4, 2020 | Curiel, David, Diamond, Michael, Dmitriev, Igor, Hassan, Ahmed
— Technology Description
Researchers at Washington University in St. Louis have developed a chimpanzee adenovirus-based vaccine for COVID-19. COVID-19, the clinical syndrome caused by SARS-CoV-2 infection, has had extensive morbidity and mortality impacts and destabilized society. There is an urg…
by | Oct 22, 2019 | Curiel, David
— Disease indication – Cancer
Drug format – Adenoviral vector for immunotherapy/dendritic cell therapy
Drug class – Improvement
Research stage and Preliminary data:
Target – Carbohydrate biomarkers of cancer
Background:
Dendritic cells (DCs) are potent antigen presenting cell…