C3-knockout mice
— Genetic disruption of murine C3 promotor region generates deficient mice with extrahepatic expression of C3 mRNA
Crry-deficient mouse strain
— Crry-knockout mouse strain (Crry -/-)
Researchers generated mice deficient in Crry by disrupting exon 5 of the mouse Crry gene. The mice are sensitive to complement deposition and activation, especially the C3 component of complement on the surface of the placenta.
Publication: A Critical Role for Murine Complement Regulator Crry in Fe…
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