System and Method for Non-invasive Brain Stimulation for Cognitive Enhancement

Tech ID: T-020194

Published date: 3/3/2026

Value Proposition: Non-invasive platform that can increase cognitive function in humans.

Technology Description

Researchers at Washington University in St. Louis have developed a system that enables near- real-time control of human brain activity using non-invasive transcranial electrical current stimulation (tECS). The invention uses a computational brain modeling method to allow for optimal control of brain activity that is explicitly linked to specific cognitive behaviors, including manipulation of large-scale brain networks. In contrast to existing tECS systems, this method combines a hardware software solution which allows for both pre-programmed and responsive stimulation and low-latency delivery of tCES to the human scalp, thus allowing for closed loop stimulation designs.

Stage of Research

Proposed 60 patient Trial

Applications

  • Intervention for individuals with neurological and mental health disorders associated with cognitive impairment

  • Improve higher cognitive function in humans

  • Framework can be used to conduct neurostimulation

Key Advantages

  • Enhances attention/focus caused by neuro/mental health disorders and cognitive impairment

  • Makes second-to-second determination on the appropriate stimulation current to be delivered

  • Allows for both pre-programed and responsive stimulation

Patents

Patent application filed

Related Web Links – Shinung Ching profile; Ching lab

Categories

Inventors

Contact

Weilbaecher, Craig
314-747-0685
cweilbaecher@wustl.edu

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